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Methods - Multiple single-unit recording - Leibniz Institute for Neurobiology, Magdeburg
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 Methods

 Multiple single-unit recording

We perform multiple simultaneous recordings of electrical brain activity with a multi-electrode system (Figure): Such system is commercially available. Electrodes are inserted transdurally afresh each day, and are moved to the desired brain target. Multielectrode recordings offer two advantages over standard single electrode recordings. Firstly, the activity of a larger number of single neurones can be recorded in a given amount of time than with a single electrode. Secondly, and more importantly, simultaneous recording of many cells permits analyses which cannot be carried out otherwise, for example the computation of covariance between the discharges of different cells. This analysis can be performed over different time scales and provides information on the correlation of neural firing.

 

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