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 AG Cerebral metabolism and functional small-animal-imaging

 The use of heavy metals as tracers for mapping neuronal activity

(Katja Saldeitis)

The research of this project is concerned with the functional anatomy of the auditory thalamocortical, corticothalamic and interhemispheric connections of the auditory cortex using Mongolian gerbils as model organism.

In course of this project we are studying the detailed anatomy of these systems by anterograde tract tracing techniques as well as the morphology of the axonal terminals at the light and electron microscopic level.

Furthermore, we try to understand the functional role of the above-named projection systems. This issue we are approaching by examining the learning-dependent behavioral and electrophysiological consequences of specific photolytic lesions of the respective projection neurons.

Figure: Magnocellular neurons of the medial geniculate body (left; gerbil) respond to a wide range of tone frequencies (rasterplot, middle) and project preferentially to the deep layers of several auditory fields (right).
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