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 Functional Architecture of Memory

 Projects/Techniques

Projects

* Characterization of the specific role of the MTL areas in spatial or non-spatial recognition memory depending on visual or olfactory sensory modalities (behavior, brain lesion and neuroanatomical brain imaging)
* Evaluation of memory performance and study of the reorganization of the MTL areas following brain injury in models of amnesia (behavior, brain lesion and neuroanatomical brain imaging)
* Characterization of memory performance and brain alterations in models of aging (behavior and neuroanatomical brain imaging)
* Development of behavioral translational memory paradigms and fMRI cognitive translational paradigms in awake rodents (behavior, stereotactic surgery, animal fMRI)

Techniques

* Translational olfactory memory tasks based on psychophysics
* Standard behavioral spatial and non-spatial object recognition paradigms in rats and mice
* Optogenetic techniques
* Use of mutant mice models
* Intracerebral injections, brain lesions with microglass pipettes
* Molecular imaging (in-situ hybridization, immunocytochemistry, histology)
* fMRI in awake rodents
* Stereotactic surgery
* in-vivo electrophysiology

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