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 Neurochemistry & Molecular Biology

 AG Chemical Synapses

Prof Dr. Eckart D. Gundelfinger

Department Neurochemistry and Molecular Biology
Leibniz Institute for Neurobiology
Brenneckestraße 6
39118 Magdeburg
Phone:     +49-391-6263-93311, 93321
Fax:         +49-391-6263-93319
E-mail:     Eckart.Gundelfinger@lin-magdeburg.de


Neurotransmitter release from presynaptic boutons occurs at specialized regions of the plasma membrane, the active zones. These structures are characterized by a dense protein cytomatrix, the components of which are involved in the regulation of multiple presynaptic functions (Gundelfinger & Fejtova, 2012). Our interest focuses on mechanisms underlying the formation, function and plasticity of these presynaptic specializations using molecular and cellular approaches and mouse genetics.

Molecular organization of the active zone

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PDF The Active Zone





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