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Research - Neuronal Cirquits - Leibniz Institute for Neurobiology, Magdeburg
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 Research

 Neuronal Cirquits

Immunocytochemical investigations with marker proteins for cellular activity have shown a frequency-specific induction of the 'immediate early gene' protein product c-Fos in neurons of the primary auditory cortex following acoustic stimulation. Commonly, c-Fos immunoreactive cells formed columns and cell clusters through all layers except layer I (Picture 93 kB) (Zuschratter et al., 1995).

To further characterize the chemical identity of the labeled neurons and to get insights into the input- and output-projections of the stimulated neurons, c-Fos expressing cells were tested for a coexistence with calcium-binding proteins parvalbumin (PV) or calbindin D28K (CALB) and immunostaining was combined with tracing experiments (Picture 131 kB)

c-Fos immunoreactive cells formed columns and cell clusters through all layers except layer I (93 kB)
131 kB
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