Person Details
- Prof. Dr. Frank Angenstein
- Leibniz Institute for Neurobiology
- Brenneckestr. 6
- 39118 Magdeburg
- Germany
- Telefon :
- +49 391 6263 92091
- E-Mail :
- angstein@lin-magdeburg.de
-
Publikationen
Angenstein F 2014 The actual intrinsic excitability of granular cells determines the ruling neurovascular coupling mechanism in the rat dentate gyrus Journal of Neuroscience 34 25 8529-8545https://doi.org/10.1523/JNEUROSCI.0472-14.2014
Helbing C, Werner G, Angenstein F 2013 Variations in the temporal pattern of perforant pathway stimulation control the activity in the mesolimbic pathway NeuroImage 64 1 43-60https://doi.org/10.1016/j.neuroimage.2012.09.001
Krautwald K, Min H, Lee K, Angenstein F 2013 Synchronized electrical stimulation of the rat medial forebrain bundle and perforant pathway generates an additive BOLD response in the nucleus accumbens and prefrontal cortex NeuroImage 77 14-25https://doi.org/10.1016/j.neuroimage.2013.03.046
Pachow D, Andrae N, Kliese N, Angenstein F, Stork O, Wilisch-Neumann A, Kirches E, Mawrin C 2013 MTORC1 inhibitors suppress meningioma growth in mouse models Clinical Cancer Research 19 5 1180-1189https://doi.org/10.1158/1078-0432.CCR-12-1904
Kolodziej A, Lippert M, Angenstein F, Neubert J, Pethe A, Grosser O, Amthauer H, Schröder U, Reymann K, Scheich H, Ohl F, Goldschmidt J 2014 SPECT-imaging of activity-dependent changes in regional cerebral blood flow induced by electrical and optogenetic self-stimulation in mice NeuroImage 103 171-180https://doi.org/10.1016/j.neuroimage.2014.09.023
Szabó B, Török J, Somfai E, Wegner S, Stannarius R, Böse A, Rose G, Angenstein F, Börzsönyi T 2014 Evolution of shear zones in granular materials Physical Review E 90 3https://doi.org/10.1103/PhysRevE.90.032205
Haroon F, Händel U, Angenstein F, Goldschmidt J, Kreutzmann P, Lison H, Fischer K, Scheich H, Wetzel W, Schlüter D, Budinger E 2012 Toxoplasma gondii actively inhibits neuronal function in chronically infected mice PLoS ONE 7 4 e35516https://doi.org/10.1371/journal.pone.0035516
Krautwald K, Angenstein F 2012 Low frequency stimulation of the perforant pathway generates anesthesia-specific variations in neural activity and BOLD responses in the rat dentate gyrus Journal of Cerebral Blood Flow and Metabolism 32 2 291-305https://doi.org/10.1038/jcbfm.2011.126
Tiede R, Krautwald K, Fincke A, Angenstein F 2012 NMDA-dependent mechanisms only affect the BOLD response in the rat dentate gyrus by modifying local signal processing Journal of Cerebral Blood Flow and Metabolism 32 3 570-584https://doi.org/10.1038/jcbfm.2011.182
Börzsönyi T, Unger T, Szabó B, Wegner S, Angenstein F, Stannarius R 2011 Reflection and exclusion of shear zones in inhomogeneous granular materials Soft Matter 7 18 8330-8336https://doi.org/10.1039/c1sm05762f
Heyden A, Ionescu M, Romorini S, Kracht B, Ghiglieri V, Calabresi P, Angenstein F, Gundelfinger E 2011 Hippocampal enlargement in Bassoon-mutant mice is associated with enhanced neurogenesis, reduced apoptosis, and abnormal BDNF levels Cell and Tissue Research 346 1 11-26https://doi.org/10.1007/s00441-011-1233-3
Koch D, Spiwoks-Becker I, Sabanov V, Sinning A, Dugladze T, Stellmacher A, Ahuja R, Grimm J, Schüler S, Müller A, Angenstein F, Ahmed T, Diesler A, Moser M, Dieck S, Spessert R, Boeckers T, Fässler R, Hübner C, Balschun D, Gloveli T, Kessels M, Qualmann B 2011 Proper synaptic vesicle formation and neuronal network activity critically rely on syndapin i EMBO Journal 30 24 4955-4969https://doi.org/10.1038/emboj.2011.339
Angenstein F, Krautwald K, Scheich H 2010 The current functional state of local neuronal circuits controls the magnitude of a BOLD response to incoming stimuli NeuroImage 50 4 1364-1375https://doi.org/10.1016/j.neuroimage.2010.01.070
Angenstein F, Kammerer E, Scheich H 2009 The BOLD response in the rat hippocampus depends rather on local processing of signals than on the input or output activity. A combined functional MRI and electrophysiological study Journal of Neuroscience 29 8 2428-2439https://doi.org/10.1523/JNEUROSCI.5015-08.2009
Behr B, Schnabel R, Mirastschijski U, Ibrahim B, Angenstein F, Schneider W 2009 Magnetic resonance imaging monitoring of peripheral nerve regeneration following neurotmesis at 4.7 tesla Plastic and Reconstructive Surgery 123 6 1778-1788https://doi.org/10.1097/PRS.0b013e3181a3f343
Fischer D, Finger T, Angenstein F, Stannarius R 2009 Diffusive and subdiffusive axial transport of granular material in rotating mixers Physical Review E 80 6https://doi.org/10.1103/PhysRevE.80.061302
Frisch C, Hüsch K, Angenstein F, Kudin A, Kunz W, Elger C, Helmstaedter C 2009 Dose-dependent memory effects and cerebral volume changes after in utero exposure to valproate in the rat Epilepsia 50 6 1432-1441https://doi.org/10.1111/j.1528-1167.2008.01943.x
Angenstein F, Hilfert L, Niessen H, Gundelfinger E 2008 Morphological and metabolic changes in the cortex of mice lacking the functional presynaptic active zone protein bassoon Cerebral Cortex 18 4 890-897https://doi.org/10.1093/cercor/bhm122
Heyden A, Angenstein F, Sallaz M, Montag D 2008 Abnormal axonal guidance and brain anatomy in mouse mutants for the cell recognition molecules close homolog of L1 and NgCAM-related cell adhesion molecule Neuroscience 155 1 221-233https://doi.org/10.1016/j.neuroscience.2008.04.080
Angenstein F, Kammerer E, Niessen H, Frey J, Scheich H, Frey S 2007 Frequency-dependent activation pattern in the rat hippocampus, a simultaneous electrophysiological and fMRI study NeuroImage 38 1 150-163https://doi.org/10.1016/j.neuroimage.2007.07.022
Niessen H, Debska-Vielhaber G, Sander K, Angenstein F, Ludolph A, Hilfert L, Willker W, Leibfritz D, Heinze H, Kunz W, Vielhaber S 2007 Metabolic progression markers of neurodegeneration in the transgenic G93A-SOD1 mouse model of amyotrophic lateral sclerosis European Journal of Neuroscience 25 6 1669-1677https://doi.org/10.1111/j.1460-9568.2007.05415.x
Deutscher A, Niessen H, Angenstein F, Goldschmidt J, Scheich H, Schulze H 2006 Comparison of estimates for volumes of brain ablations derived from structural MRI and classical histology Journal of Neuroscience Methods 156 1-2 136-139https://doi.org/10.1016/j.jneumeth.2006.02.009
Scherf T, Angenstein F 2015 Postsynaptic and spiking activity of pyramidal cells, the principal neurons in the rat hippocampal CA1 region, does not control the resultant BOLD response Journal of Cerebral Blood Flow and Metabolism 35 4 565-575https://doi.org/10.1038/jcbfm.2014.252
Angenstein F, Niessen H, Goldschmidt J, Lison H, Gundelfinger E, Scheich H 2007 Manganese-enhanced MRI reveals structural and functional changes in the cortex of bassoon mutant mice Cerebral Cortex 17 1 28-36https://doi.org/10.1093/cercor/bhj121
Hunger M, Budinger E, Zhong K, Angenstein F 2014 Visualization of acute focal lesions in rats with experimental autoimmune encephalomyelitis by magnetic nanoparticles, comparing different MRI sequences including phase imaging Journal of Magnetic Resonance Imaging 39 5 1126-1135https://doi.org/10.1002/jmri.24280
Kliese N, Gobrecht P, Pachow D, Andrae N, Wilisch-Neumann A, Kirches E, Riek-Burchardt M, Angenstein F, Reifenberger G, Riemenschneider M, Meese E, Panayotova-Dimitrova D, Gutmann D, Mawrin C 2013 MiRNA-145 is downregulated in atypical and anaplastic meningiomas and negatively regulates motility and proliferation of meningioma cells Oncogene 32 39 4712-4720https://doi.org/10.1038/onc.2012.468
Schreiber S, Bueche C, Garz C, Kropf S, Angenstein F, Goldschmidt J, Neumann J, Heinze H, Görtler M, Reymann K, Braun H 2012 The pathologic cascade of cerebrovascular lesions in SHRSP Journal of Cerebral Blood Flow and Metabolism 32 2 278-290https://doi.org/10.1038/jcbfm.2011.122
Angenstein F, Richter K, Gundelfinger E, Staak S 1998 Identification of fucose α(1-2) galactose epitope-containing glycoproteins from rat hippocampus NeuroReport 9 5 813-817https://doi.org/10.1097/00001756-199803300-00009
Niessen H, Angenstein F, Sander K, Kunz W, Teuchert M, Ludolph A, Heinze H, Scheich H, Vielhaber S 2006 In vivo quantification of spinal and bulbar motor neuron degeneration in the G93A-SOD1 transgenic mouse model of ALS by T2 relaxation time and apparent diffusion coefficient Experimental Neurology 201 2 293-300https://doi.org/10.1016/j.expneurol.2006.04.007
Niessen H, Angenstein F, Vielhaber S, Frisch C, Kudin A, Elger C, Heinze H, Scheich H, Kunz W 2005 Volumetric magnetic resonance imaging of functionally relevant structural alterations in chronic epilepsy after pilocarpine-induced status epilepticus in rats Epilepsia 46 7 1021-1026https://doi.org/10.1111/j.1528-1167.2005.60704.x
Angenstein F, Niessen H, Goldschmidt J, Vielhaber S, Ludolph A, Scheich H 2004 Age-dependent changes in MRI of motor brain stem nuclei in a mouse model of ALS NeuroReport 15 14 2271-2274https://doi.org/10.1097/00001756-200410050-00026
Angenstein F, Krautwald K, Wetzel W, Scheich H 2013 Perforant pathway stimulation as a conditioned stimulus for active avoidance learning triggers BOLD responses in various target regions of the hippocampus NeuroImage 75 213-227https://doi.org/10.1016/j.neuroimage.2013.03.007
Angenstein F, Riedel G, Reymann K, Staak S 1999 Transient translocation of protein kinase Cγ in hippocampal long-term potentiation depends on activation of metabotropic glutamate receptors Neuroscience 93 4 1289-1295https://doi.org/10.1016/S0306-4522(99)00315-2
Dudanova I, Sedej S, Ahmad M, Masius H, Sargsyan V, Zhang W, Riedel D, Angenstein F, Schild D, Rupnik M, Missler M 2006 Important contribution of α-neurexins to Ca2+-triggered exocytosis of secretory granules Journal of Neuroscience 26 41 10599-10613https://doi.org/10.1523/JNEUROSCI.1913-06.2006
Spilker C, Nullmeier S, Grochowska K, Schumacher A, Butnaru I, Macharadze T, Gomes G, Yuanxiang P, Bayraktar G, Rodenstein C, Geiseler C, Kolodziej A, Lopez-Rojas J, Montag D, Angenstein F, Bär J, D’Hanis W, Roskoden T, Mikhaylova M, Budinger E, Ohl F, Stork O, Zenclussen A, Schwegler H, Kreutz M 2016 A Jacob/Nsmf Gene Knockout Results in Hippocampal Dysplasia and Impaired BDNF Signaling in Dendritogenesis PLoS Genetics 12 3https://doi.org/10.1371/journal.pgen.1005907
Radtke-Schuller S, Schuller G, Angenstein F, Grosser O, Goldschmidt J, Budinger E 2016 Brain atlas of the Mongolian gerbil (Meriones unguiculatus) in CT/MRI-aided stereotaxic coordinates Brain Structure and Function 221 Suppl 1 Suppl. 1 1-272https://doi.org/10.1007/s00429-016-1259-0
Bhattacharya S, Herrera-Molina R, Sabanov V, Ahmed T, Iscru E, Stöber F, Richter K, Fischer K, Angenstein F, Goldschmidt J, Beesley P, Balschun D, Gundelfinger E, Montag D 2017 Genetically induced retrograde amnesia of associative memories after neuroplastin ablation Biological Psychiatry 81 2 124-135https://doi.org/10.1016/j.biopsych.2016.03.2107
Helbing C, Brocka M, Scherf T, Lippert M, Angenstein F 2016 The role of the mesolimbic dopamine system in the formation of blood-oxygen-level dependent responses in the medial prefrontal/anterior cingulate cortex during high-frequency stimulation of the rat perforant pathway Journal of Cerebral Blood Flow and Metabolism 36 12 2177-2193https://doi.org/10.1177/0271678X15615535
Riemann S, Helbing C, Angenstein F 2017 From unspecific to adjusted, how the BOLD response in the rat hippocampus develops during consecutive stimulations Journal of Cerebral Blood Flow and Metabolism 37 2 590-604https://doi.org/10.1177/0271678X16634715
Angenstein F, Matthies H, Reymann K, Staak S 1992 The maintenance of hippocampal long-term potentiation is paralleled by a dopamine-dependent increase in glycoprotein fucosylation Neurochemistry International 21 3 403-408https://doi.org/10.1016/0197-0186(92)90191-S
Staak S, Angenstein F 1995 Hippocampal long-term potentiation Brain Research 682 1-2 55-62https://doi.org/10.1016/0006-8993(95)00319-L
Angenstein F, Staak S 1997 Activation of metabotropic glutamate receptors increases endogenous protein kinase C substrate phosphorylation in adult hippocampal slices Brain Research 745 1-2 46-54https://doi.org/10.1016/S0006-8993(96)01129-8
Angenstein F, Staak S 1997 Receptor-mediated activation of protein kinase C in hippocampal long-term potentiation Progress in Neuro-Psychopharmacology and Biological Psychiatry 21 3 427-454https://doi.org/10.1016/S0278-5846(97)00012-2
Angenstein F, Staak S 1992 Phorbol ester-induced changes in rat hippocampal glycoprotein fucosylation Neuroscience Letters 135 2 269-272https://doi.org/10.1016/0304-3940(92)90453-E
Scherf T, Angenstein F 2017 Hippocampal CA3 activation alleviates fMRI-BOLD responses in the rat prefrontal cortex induced by electrical VTA stimulation PLoS ONE 12 2https://doi.org/10.1371/journal.pone.0172926
Angenstein F, Staak S 1999 Age-dependent differences in glutamate-induced phosphorylation systems in rat hippocampal slices Hippocampus 9 2 173-185https://doi.org/10.1002/(SICI)1098-1063(1999)9:2<173::AID-HIPO8>3.0.CO;2-K
Helbing C, Tischmeyer W, Angenstein F 2017 Late effect of dopamine D<sub>1/5</sub> receptor activation on stimulus-induced BOLD responses in the hippocampus and its target regions depends on the history of previous stimulations NeuroImage 152 119-129https://doi.org/10.1016/j.neuroimage.2017.02.077
Pöttker B, Stöber F, Hummel R, Angenstein F, Radyushkin K, Goldschmidt J, Schäfer M 2017 Traumatic brain injury causes long-term behavioral changes related to region-specific increases of cerebral blood flow Brain Structure and Function 222 9 4005-4021https://doi.org/10.1007/s00429-017-1452-9
Henschke J, Angenstein F, Ohl F, Goldschmidt J, Kanold P, Budinger E 2018 Early sensory experience influences the development of multisensory thalamocortical and intracortical connections of primary sensory cortices Brain Structure and Function 223 3 1165-1190https://doi.org/10.1007/s00429-017-1549-1
Brocka M, Helbing C, Vincenz D, Scherf T, Montag D, Goldschmidt J, Angenstein F, Lippert M 2018 Contributions of dopaminergic and non-dopaminergic neurons to VTA-stimulation induced neurovascular responses in brain reward circuits NeuroImage 177 88-97https://doi.org/10.1016/j.neuroimage.2018.04.059
Bovet-Carmona M, Menigoz A, Pinto S, Tambuyzer T, Krautwald K, Voets T, Aerts J, Angenstein F, Vennekens R, Balschun D 2018 Disentangling the role of TRPM4 in hippocampus-dependent plasticity and learning Brain Structure and Function 223 8 3557-3576https://doi.org/10.1007/s00429-018-1706-1
Caliskan G, Müller S, Montag D, Budinger E, Angenstein F, Fejtova A, Tischmeyer W, Gundelfinger E, Stork O 2018 Ablation of the presynaptic organizer Bassoon in excitatory neurons retards dentate gyrus maturation and enhances learning performance Brain Structure and Function 223 7 3423-3445https://doi.org/10.1007/s00429-018-1692-3
Bovet-Carmona M, Krautwald K, Menigoz A, Vennekens R, Balschun D, Angenstein F 2019 Low frequency pulse stimulation of Schaffer collaterals in Trpm4<sup>−/−</sup> knockout rats differently affects baseline BOLD signals in target regions of the right hippocampus but not BOLD responses at the site of stimulation NeuroImage 188 347-356https://doi.org/10.1016/j.neuroimage.2018.12.020
Krautwald K, Mahnke L, Angenstein F 2019 Electrical Stimulation of the Lateral Entorhinal Cortex Causes a Frequency-Specific BOLD Response Pattern in the Rat Brain Frontiers in Neuroscience 13 MAYhttps://doi.org/10.3389/fnins.2019.00539
Angenstein F 2019 The role of ongoing neuronal activity for baseline and stimulus-induced BOLD signals in the rat hippocampus NeuroImage 202https://doi.org/10.1016/j.neuroimage.2019.116082