LIN Personal

Grochowska KM, Gomes GM, Raman R, Kaushik R, Sosulina L, Kaneko H, Oelschlegel AM, Yuanxiang P, Reyes-Resina I, Bayraktar G, et al. 2023. Jacob-induced transcriptional inactivation of CREB promotes Aβ-induced synapse loss in Alzheimer's disease. The EMBO journal. 42(4):Article e112453. https://doi.org/10.15252/embj.2022112453

Gomes GM, Bär J, Karpova A, Kreutz MR. 2023. A Jacob/nsmf gene knockout does not protect against acute hypoxia- and NMDA-induced excitotoxic cell death. Molecular brain. 16(1):Article 23. https://doi.org/10.1186/s13041-023-01012-2

Confettura AD, Cuboni E, Ammar MR, Jia S, Gomes GM, Yuanxiang P, Raman R, Li T, Grochowska KM, Ahrends R, et al. 2022. Neddylation-dependent protein degradation is a nexus between synaptic insulin resistance, neuroinflammation and Alzheimer's disease. Translational neurodegeneration. 11(1):Article 2. https://doi.org/10.1186/s40035-021-00277-8

Grochowska KM, Bär J, Gomes GM, Kreutz MR, Karpova A. 2021. Jacob, a Synapto-Nuclear Protein Messenger Linking N-methyl-D-aspartate Receptor Activation to Nuclear Gene Expression. Frontiers in Synaptic Neuroscience. 13:Article 787494. https://doi.org/10.3389/fnsyn.2021.787494

Borgmeyer M, Coman C, Has C, Schött H-F, Li T, Westhoff P, Cheung YFH, Hoffmann N, Yuanxiang P, Behnisch T, et al. 2021. Multiomics of synaptic junctions reveals altered lipid metabolism and signaling following environmental enrichment. Cell Reports. 37(1):Article 109797. https://doi.org/10.1016/j.celrep.2021.109797

Bayraktar G, Yuanxiang P, Confettura AD, Gomes GM, Raza SA, Stork O, Tajima S, Suetake I, Karpova A, Yildirim F, et al. 2020. Synaptic control of DNA methylation involves activity-dependent degradation of DNMT3A1 in the nucleus. Neuropsychopharmacology. 45(12):2120-2130. https://doi.org/10.1038/s41386-020-0780-2

Andres-Alonso M, Ammar MR, Butnaru I, Gomes GM, Acuña Sanhueza G, Raman R, Yuanxiang P, Borgmeyer M, Lopez-Rojas J, Raza SA, et al. 2019. SIPA1L2 controls trafficking and local signaling of TrkB-containing amphisomes at presynaptic terminals. Nature Communications. 10(1):Article 5448. https://doi.org/10.1038/s41467-019-13224-z

Spilker C, Nullmeier S, Grochowska KM, Schumacher A, Butnaru I, Macharadze T, Gomes GM, YuanXiang P, Bayraktar G, Rodenstein C, et al. 2016. A Jacob/Nsmf Gene Knockout Results in Hippocampal Dysplasia and Impaired BDNF Signaling in Dendritogenesis. PLoS Genetics. 12(3):Article e1005907. https://doi.org/10.1371/journal.pgen.1005907

Gomes GM, Dalmolin GD, Bär J, Karpova A, Mello CF, Kreutz MR, Rubin MA. 2014. Inhibition of the polyamine system counteracts β-amyloid peptide-induced memory impairment in mice: Involvement of extrasynaptic NMDA receptors. PLoS ONE. 9(6):Article e99184. https://doi.org/10.1371/journal.pone.0099184