LIN Personal

Dr. Hongbo Jia

Leiter

Combinatorial NeuroImaging

Leibniz-Institut für Neurobiologie
Brenneckestr. 6
39118 Magdeburg
Deutschland
Telefon: +49 391 6263 93331
E-Mail: Hongbo.Jia@lin-magdeburg.de
ORCID: 0000-0003-1585-2161

  • Publikationen

    Publikationen

    Yang M, Zhou Z-Q, Lang S, Zheng H, Chen S, Li T, Stas E, Yu J, Zhang L, Zhang Z, et al. 2026. Ultra-wide-field, deep, adaptive two-photon microscopy for multi-scale neuronal imaging. Light: Science and Applications. 15(1):Article 198. https://doi.org/10.1038/s41377-026-02252-2

    Wang Z, Zhu J, Wang Y, Hu T, Chen S, Xu S, Li Y, Liao X, Liang S, Li Y, et al. 2026. Non-invasive and painless mid-infrared modulation increases collagen in human and mouse skin. Journal of advanced research. https://doi.org/10.1016/j.jare.2026.01.069

    Chen S, Yang M, Lyu J, Huang Y, Ye H, Gao Q, Chen T, Chen H, Zeng H, Li M, et al. 2026. Cellular multipoint adaptive technology for two-photon mesoscope. Neurophotonics. 13(1):Article 015004. https://doi.org/10.1117/1.NPh.13.1.015004

    Qin H, Jian T, Jin W, Liang M, Liao X, Zhang K, Liang S, Zhang C, He C, Jia H, et al. 2026. A hypothalamo-septo-hippocampal circuit for REM sleep-dependent consolidation of social memory. bioRxiv. https://doi.org/10.64898/2026.01.13.699230

    Gu M, Liang S, Zhu J, Li R, Liu K, Wang X, Ohl FW, Zhang Y, Liao X, Zhang C, et al. 2025. Tonotopy is not preserved in a descending stage of auditory cortex. eLife. 13:Article RP99989. https://doi.org/10.7554/eLife.99989

    Aly AAA, Jia H, Kreutz MR, Karpova A. 2025. Activity-dependent control of axonal amphisome trafficking governs norepinephrine release in vivo. bioRxiv. https://doi.org/10.1101/2025.09.23.677999

    Tang X, Zhao Z, Li L, Tao J, Chen Y, Polat M, Yang Z, Wei Z, Liang S, Zhang K, et al. 2025. Parvalbumin interneurons are essential for tonotopy strength in the auditory cortex. Science Bulletin. 70(17):2824-2835. https://doi.org/10.1016/j.scib.2025.06.020

    Zhang Y, Chen-Engerer H-J, Zhang K, Zott B, Varga Z, Chen Y, Chen X, Jia H, Sakmann B, Nelken I, et al. 2025. Amyloid β-dependent neuronal silencing through synaptic decoupling. Proceedings of the National Academy of Sciences of the United States of America. 122(35):Article e2515113122. https://doi.org/10.1073/pnas.2515113122

    Jia H, Wang M, Pakan JMP, Li SC, Chen X. 2025. Burst firing represents learned composite stimuli in primary sensory cortices. Current Opinion in Neurobiology. 93:Article 103039. https://doi.org/10.1016/j.conb.2025.103039

    Zhao Z, Tang X, Chen Y, Tao J, Polat M, Yang Z, Yang L, Wang M, Liang S, Zhang K, et al. 2025. A parallel tonotopically arranged thalamocortical circuit for sound processing. Neuron. 113(12):1998-2013.e6. https://doi.org/10.1016/j.neuron.2025.03.022

    Yang M, Zhou Z-Q, Lang S, Zheng H, Chen S, Li T, Stas E, Zhang L, Zhang Z, Uzungil V, et al. 2025. Ultra-wide-field, deep, adaptive two-photon microscopy. bioRxiv. https://doi.org/10.1101/2025.06.07.658419

    Zou Y, Yang L, Zhu J, Fan J, Zheng H, Liao X, Yang Z, Zhang K, Jia H, Konnerth A, et al. 2025. Pitolisant alleviates brain network dysfunction and cognitive deficits in a mouse model of Alzheimer's disease. Translational Psychiatry. 15(1):Article 126. https://doi.org/10.1038/s41398-025-03358-8

    Liu Y, Gao Z, Xu Z, Yang C, Sun P, Li L, Jia H, Chen X, Liao X, Pan J, et al. 2025. Brain-wide 3D neuron detection and mapping with deep learning. Neurophotonics. 12(2):Article 025012. https://doi.org/10.1117/1.NPh.12.2.025012

    Shi T, Ullah R, Jia H. 2025. Speech enhancement based on emphasizing the fundamental frequency integrated with SNMF/DNN. Multimedia Tools and Applications. 84(14):13157-13175. https://doi.org/10.1007/s11042-024-19464-6

    Pan J, Yang C, Li R, Li J, Sun P, Liu Y, Liu K, Liao X, Jia H, Yu Z, et al. 2025. Brain-wide atlas of outputs and inputs of mouse auditory cortex revealed by modified viral labeling strategies. Fundamental Research. https://doi.org/10.1016/j.fmre.2025.08.014

    Jia X, Jia H. 2024. Off-axis freeform optical design for large curved field of view imaging. Applied Optics. 63(31):8152-8163. https://doi.org/10.1364/AO.536986

    Wu S, Li M, Jia H. 2024. Adaptive multi-surrogate model for complex opto-mechanical system alignment. Optics Express. 32(21):37211-37223. https://doi.org/10.1364/OE.531314

    Li X, Li X, Li J, Qin H, Liang S, Li J, Jian T, Wang X, Yin L, Yuan C, et al. 2024. Brainstem neurons coordinate the bladder and urethra sphincter for urination. bioRxiv. https://doi.org/10.1101/2024.10.01.616107

    Wu Y, Xu Z, Liang S, Wang L, Wang M, Jia H, Chen X, Zhao Z, Liao X. 2024. NeuroSeg-III: efficient neuron segmentation in two-photon Ca2+ imaging data using self-supervised learning. Biomedical Optics Express. 15(5):2910-2925. https://doi.org/10.1364/BOE.521478

    Li R, Huang J, Li L, Zhao Z, Liang S, Liang S, Wang M, Liao X, Lyu J, Zhou Z, et al. 2023. Holistic bursting cells store long-term memory in auditory cortex. Nature Communications. 14(1):Article 8090. https://doi.org/10.1038/s41467-023-43620-5

    Li X, Song S, Yao J, Liao X, Chen M, Zhai J, Lang L, Lin C, Zhang N, Yuan C, et al. 2023. Autofluorescence spectral analysis for detecting urinary stone composition in emulated intraoperative ambient. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 300:Article 122913. https://doi.org/10.1016/j.saa.2023.122913

    Lyu J, Ren L, Liu Q, Wang Y, Zhou Z, Chen Y, Jia H, Tang Y, Li M. 2023. PDTANet: a context-guided and attention-aware deep learning method for tumor segmentation of guinea pig colorectal OCT images. Optics Continuum. 2(7):1716-1734. https://doi.org/10.1364/OPTCON.493630

    Gu M, Li X, Liang S, Zhu J, Sun P, He Y, Yu H, Li R, Zhou Z, Lyu J, et al. 2023. Rabies virus-based labeling of layer 6 corticothalamic neurons for two-photon imaging in vivo. iScience. 26(5):Article 106625. https://doi.org/10.1016/j.isci.2023.106625

    Li R, Wang S, Lyu J, Chen K, Sun X, Huang J, Sun P, Liang S, Li M, Yang M, et al. 2023. Ten-kilohertz two-photon microscopy imaging of single-cell dendritic activity and hemodynamics in vivo. Neurophotonics. 10(2):Article 025006. https://doi.org/10.1117/1.NPh.10.2.025006

    Huang J, Liang S, Li L, Li X, Liao X, Hu Q, Zhang C, Jia H, Chen X, Wang M, et al. 2023. Daily two-photon neuronal population imaging with targeted single-cell electrophysiology and subcellular imaging in auditory cortex of behaving mice. Frontiers in Cellular Neuroscience. 17:Article 1142267. https://doi.org/10.3389/fncel.2023.1142267

    Huang W, Wang Y, Qin J, He C, Li Y, Wang Y, Li M, Lyu J, Zhou Z, Jia H, et al. 2023. A corticostriatal projection for sound-evoked and anticipatory motor behavior following temporal expectation. NeuroReport. 34(1):1-8. https://doi.org/10.1097/WNR.0000000000001851

    Huang J, Zhou Z, Li M, Jia H. 2023. 用 于 小 鼠 脑 皮 层 双 光 子 成 像 的 大 视 场 弯 曲 视 野离 轴 三 反 系 统 设 计. Guangxue Xuebao/Acta Optica Sinica. 43(1):Article 0122001. https://doi.org/10.3788/AOS221159

    Qin H, Fu L, Jian T, Jin W, Liang M, Li J, Chen Q, Yang X, Du H, Liao X, et al. 2022. REM sleep-active hypothalamic neurons may contribute to hippocampal social-memory consolidation. Neuron. 110(23):4000-4014.e6. https://doi.org/10.1016/j.neuron.2022.09.004

    Ding F, Liang S, Li R, Yang Z, He Y, Yang S, Duan Q, Zhang J, Lyu J, Zhou Z, et al. 2022. Astrocytes exhibit diverse Ca2+ changes at subcellular domains during brain aging. Frontiers in Aging Neuroscience. 14:Article 1029533. https://doi.org/10.3389/fnagi.2022.1029533

    Tang J, Xue R, Wang Y, Li M, Jia H, Pakan JMP, Li L, Chen X, Li X. 2022. Optical Fiber-Based Recording of Climbing Fiber Ca2+ Signals in Freely Behaving Mice. Biology. 11(6):Article 907. https://doi.org/10.3390/biology11060907

    Wang M, Liu K, Pan J, Li J, Sun P, Zhang Y, Li L, Guo W, Xin Q, Zhao Z, et al. 2022. Brain-wide projection reconstruction of single functionally defined neurons. Nature Communications. 13(1):Article 1531. https://doi.org/10.1038/s41467-022-29229-0

    He C, Li Q, Cui Y, Gao P, Shu W, Zhou Q, Wang L, Li L, Lu Z, Zhao Y, et al. 2022. Recurrent moderate hypoglycemia accelerates the progression of Alzheimer's disease through impairment of the TRPC6/GLUT3 pathway. JCI Insight. 7(5):Article e154595. https://doi.org/10.1172/jci.insight.154595

    Zhang J, He Y, Liang S, Liao X, Li T, Qiao Z, Chang C, Jia H, Chen X. 2021. Non-invasive, opsin-free mid-infrared modulation activates cortical neurons and accelerates associative learning. Nature Communications. 12(1):2730. https://doi.org/10.1038/s41467-021-23025-y

    Li Z, Wu M, Yao J, Guo J, Liao X, Song S, Li J, Duan G, Zhou Y, Wu X, et al. 2020. Caution on Kidney Dysfunctions of COVID-19 Patients. medRxiv. https://doi.org/10.1101/2020.02.08.20021212

    Yang M, Zhou Z, Zhang J, Jia S, Li T, Guan J, Liao X, Leng B, Lyu J, Zhang K, et al. 2019. MATRIEX imaging: multiarea two-photon real-time in vivo explorer. Light: Science and Applications. 8(1):Article 109. https://doi.org/10.1038/s41377-019-0219-x

    Yao J, Zhang Q, Liao X, Li Q, Liang S, Li X, Zhang Y, Li X, Wang H, Qin H, et al. 2018. A corticopontine circuit for initiation of urination. Nature Neuroscience. 21(11):1541-1550. https://doi.org/10.1038/s41593-018-0256-4

    Li Q, Jin R, Yu H, Lang H, Cui Y, Xiong S, Sun F, He C, Liu D, Jia H, et al. 2018. Enhancement of Neural Salty Preference in Obesity. Cellular Physiology and Biochemistry. 43(5):1987-2000. https://doi.org/10.1159/000484122

    Guan J, Li J, Liang S, Li R, Li X, Shi X, Huang C, Zhang J, Pan J, Jia H, et al. 2018. NeuroSeg: automated cell detection and segmentation for in vivo two-photon Ca2+ imaging data. Brain Structure and Function. 223(1):519-533. https://doi.org/10.1007/s00429-017-1545-5

    Zhang Q, Yao J, Guang Y, Liang S, Guan J, Qin H, Liao X, Jin W, Zhang J, Pan J, et al. 2017. Locomotion-related population cortical Ca2+ transients in freely behaving mice. Frontiers in Neural Circuits. 11:Article 24. https://doi.org/10.3389/fncir.2017.00024

    Li Q, Cui Y, Jin R, Lang H, Yu H, Sun F, He C, Ma T, Li Y, Zhou X, et al. 2017. Enjoyment of spicy flavor enhances central salty-taste perception and reduces salt intake and blood pressure. Hypertension. 70(6):1291-1299. https://doi.org/10.1161/HYPERTENSIONAHA.117.09950

    Jia H, Varga Z, Sakmann B, Konnerth A. 2014. Linear integration of spine Ca2+ signals in layer 4 cortical neurons in vivo. Proceedings of the National Academy of Sciences of the United States of America. 111(25):9277-9282. https://doi.org/10.1073/pnas.1408525111

    Chen X, Leischner U, Varga Z, Jia H, Deca D, Rochefort NL, Konnerth A. 2012. LOTOS-based two-photon calcium imaging of dendritic spines in vivo. Nature Protocols. 7(10):1818-1829. https://doi.org/10.1038/nprot.2012.106

    Jia H, Rochefort NL, Chen X, Konnerth A. 2011. In vivo two-photon imaging of sensory-evoked dendritic calcium signals in cortical neurons. Nature Protocols. 6(1):28-35. https://doi.org/10.1038/nprot.2010.169

    Rochefort NL, Jia H, Konnerth A. 2008. Calcium imaging in the living brain: prospects for molecular medicine. Trends in Molecular Medicine. 14(9):389-399. https://doi.org/10.1016/j.molmed.2008.07.005
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