LIN Personal
Dr. Hongbo Jia
Leiter
Combinatorial NeuroImaging
Leibniz-Institut für NeurobiologieBrenneckestr. 6
39118 Magdeburg
Deutschland
Telefon: +49 391 6263 93331
E-Mail: Hongbo.Jia@lin-magdeburg.de
ORCID: 0000-0003-1585-2161
- Publikationen
Publikationen
Yang M, Zhou Z-Q, Lang S, Zheng H, Chen S, Li T, Stas E, Yu J, Zhang L, Zhang Z, et al. 2026. Ultra-wide-field, deep, adaptive two-photon microscopy for multi-scale neuronal imaging. Light: Science and Applications. 15(1):Article 198. https://doi.org/10.1038/s41377-026-02252-2Wang Z, Zhu J, Wang Y, Hu T, Chen S, Xu S, Li Y, Liao X, Liang S, Li Y, et al. 2026. Non-invasive and painless mid-infrared modulation increases collagen in human and mouse skin. Journal of advanced research. https://doi.org/10.1016/j.jare.2026.01.069Chen S, Yang M, Lyu J, Huang Y, Ye H, Gao Q, Chen T, Chen H, Zeng H, Li M, et al. 2026. Cellular multipoint adaptive technology for two-photon mesoscope. Neurophotonics. 13(1):Article 015004. https://doi.org/10.1117/1.NPh.13.1.015004Qin H, Jian T, Jin W, Liang M, Liao X, Zhang K, Liang S, Zhang C, He C, Jia H, et al. 2026. A hypothalamo-septo-hippocampal circuit for REM sleep-dependent consolidation of social memory. bioRxiv. https://doi.org/10.64898/2026.01.13.699230Gu M, Liang S, Zhu J, Li R, Liu K, Wang X, Ohl FW, Zhang Y, Liao X, Zhang C, et al. 2025. Tonotopy is not preserved in a descending stage of auditory cortex. eLife. 13:Article RP99989. https://doi.org/10.7554/eLife.99989Aly AAA, Jia H, Kreutz MR, Karpova A. 2025. Activity-dependent control of axonal amphisome trafficking governs norepinephrine release in vivo. bioRxiv. https://doi.org/10.1101/2025.09.23.677999Tang X, Zhao Z, Li L, Tao J, Chen Y, Polat M, Yang Z, Wei Z, Liang S, Zhang K, et al. 2025. Parvalbumin interneurons are essential for tonotopy strength in the auditory cortex. Science Bulletin. 70(17):2824-2835. https://doi.org/10.1016/j.scib.2025.06.020Zhang Y, Chen-Engerer H-J, Zhang K, Zott B, Varga Z, Chen Y, Chen X, Jia H, Sakmann B, Nelken I, et al. 2025. Amyloid β-dependent neuronal silencing through synaptic decoupling. Proceedings of the National Academy of Sciences of the United States of America. 122(35):Article e2515113122. https://doi.org/10.1073/pnas.2515113122Jia H, Wang M, Pakan JMP, Li SC, Chen X. 2025. Burst firing represents learned composite stimuli in primary sensory cortices. Current Opinion in Neurobiology. 93:Article 103039. https://doi.org/10.1016/j.conb.2025.103039Zhao Z, Tang X, Chen Y, Tao J, Polat M, Yang Z, Yang L, Wang M, Liang S, Zhang K, et al. 2025. A parallel tonotopically arranged thalamocortical circuit for sound processing. Neuron. 113(12):1998-2013.e6. https://doi.org/10.1016/j.neuron.2025.03.022Yang M, Zhou Z-Q, Lang S, Zheng H, Chen S, Li T, Stas E, Zhang L, Zhang Z, Uzungil V, et al. 2025. Ultra-wide-field, deep, adaptive two-photon microscopy. bioRxiv. https://doi.org/10.1101/2025.06.07.658419Zou Y, Yang L, Zhu J, Fan J, Zheng H, Liao X, Yang Z, Zhang K, Jia H, Konnerth A, et al. 2025. Pitolisant alleviates brain network dysfunction and cognitive deficits in a mouse model of Alzheimer's disease. Translational Psychiatry. 15(1):Article 126. https://doi.org/10.1038/s41398-025-03358-8Liu Y, Gao Z, Xu Z, Yang C, Sun P, Li L, Jia H, Chen X, Liao X, Pan J, et al. 2025. Brain-wide 3D neuron detection and mapping with deep learning. Neurophotonics. 12(2):Article 025012. https://doi.org/10.1117/1.NPh.12.2.025012Shi T, Ullah R, Jia H. 2025. Speech enhancement based on emphasizing the fundamental frequency integrated with SNMF/DNN. Multimedia Tools and Applications. 84(14):13157-13175. https://doi.org/10.1007/s11042-024-19464-6Pan J, Yang C, Li R, Li J, Sun P, Liu Y, Liu K, Liao X, Jia H, Yu Z, et al. 2025. Brain-wide atlas of outputs and inputs of mouse auditory cortex revealed by modified viral labeling strategies. Fundamental Research. https://doi.org/10.1016/j.fmre.2025.08.014Jia X, Jia H. 2024. Off-axis freeform optical design for large curved field of view imaging. Applied Optics. 63(31):8152-8163. https://doi.org/10.1364/AO.536986Wu S, Li M, Jia H. 2024. Adaptive multi-surrogate model for complex opto-mechanical system alignment. Optics Express. 32(21):37211-37223. https://doi.org/10.1364/OE.531314Li X, Li X, Li J, Qin H, Liang S, Li J, Jian T, Wang X, Yin L, Yuan C, et al. 2024. Brainstem neurons coordinate the bladder and urethra sphincter for urination. bioRxiv. https://doi.org/10.1101/2024.10.01.616107Wu Y, Xu Z, Liang S, Wang L, Wang M, Jia H, Chen X, Zhao Z, Liao X. 2024. NeuroSeg-III: efficient neuron segmentation in two-photon Ca2+ imaging data using self-supervised learning. Biomedical Optics Express. 15(5):2910-2925. https://doi.org/10.1364/BOE.521478Li R, Huang J, Li L, Zhao Z, Liang S, Liang S, Wang M, Liao X, Lyu J, Zhou Z, et al. 2023. Holistic bursting cells store long-term memory in auditory cortex. Nature Communications. 14(1):Article 8090. https://doi.org/10.1038/s41467-023-43620-5Li X, Song S, Yao J, Liao X, Chen M, Zhai J, Lang L, Lin C, Zhang N, Yuan C, et al. 2023. Autofluorescence spectral analysis for detecting urinary stone composition in emulated intraoperative ambient. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 300:Article 122913. https://doi.org/10.1016/j.saa.2023.122913Lyu J, Ren L, Liu Q, Wang Y, Zhou Z, Chen Y, Jia H, Tang Y, Li M. 2023. PDTANet: a context-guided and attention-aware deep learning method for tumor segmentation of guinea pig colorectal OCT images. Optics Continuum. 2(7):1716-1734. https://doi.org/10.1364/OPTCON.493630Gu M, Li X, Liang S, Zhu J, Sun P, He Y, Yu H, Li R, Zhou Z, Lyu J, et al. 2023. Rabies virus-based labeling of layer 6 corticothalamic neurons for two-photon imaging in vivo. iScience. 26(5):Article 106625. https://doi.org/10.1016/j.isci.2023.106625Li R, Wang S, Lyu J, Chen K, Sun X, Huang J, Sun P, Liang S, Li M, Yang M, et al. 2023. Ten-kilohertz two-photon microscopy imaging of single-cell dendritic activity and hemodynamics in vivo. Neurophotonics. 10(2):Article 025006. https://doi.org/10.1117/1.NPh.10.2.025006Huang J, Liang S, Li L, Li X, Liao X, Hu Q, Zhang C, Jia H, Chen X, Wang M, et al. 2023. Daily two-photon neuronal population imaging with targeted single-cell electrophysiology and subcellular imaging in auditory cortex of behaving mice. Frontiers in Cellular Neuroscience. 17:Article 1142267. https://doi.org/10.3389/fncel.2023.1142267Huang W, Wang Y, Qin J, He C, Li Y, Wang Y, Li M, Lyu J, Zhou Z, Jia H, et al. 2023. A corticostriatal projection for sound-evoked and anticipatory motor behavior following temporal expectation. NeuroReport. 34(1):1-8. https://doi.org/10.1097/WNR.0000000000001851Huang J, Zhou Z, Li M, Jia H. 2023. 用 于 小 鼠 脑 皮 层 双 光 子 成 像 的 大 视 场 弯 曲 视 野离 轴 三 反 系 统 设 计. Guangxue Xuebao/Acta Optica Sinica. 43(1):Article 0122001. https://doi.org/10.3788/AOS221159Qin H, Fu L, Jian T, Jin W, Liang M, Li J, Chen Q, Yang X, Du H, Liao X, et al. 2022. REM sleep-active hypothalamic neurons may contribute to hippocampal social-memory consolidation. Neuron. 110(23):4000-4014.e6. https://doi.org/10.1016/j.neuron.2022.09.004Ding F, Liang S, Li R, Yang Z, He Y, Yang S, Duan Q, Zhang J, Lyu J, Zhou Z, et al. 2022. Astrocytes exhibit diverse Ca2+ changes at subcellular domains during brain aging. Frontiers in Aging Neuroscience. 14:Article 1029533. https://doi.org/10.3389/fnagi.2022.1029533Tang J, Xue R, Wang Y, Li M, Jia H, Pakan JMP, Li L, Chen X, Li X. 2022. Optical Fiber-Based Recording of Climbing Fiber Ca2+ Signals in Freely Behaving Mice. Biology. 11(6):Article 907. https://doi.org/10.3390/biology11060907Wang M, Liu K, Pan J, Li J, Sun P, Zhang Y, Li L, Guo W, Xin Q, Zhao Z, et al. 2022. Brain-wide projection reconstruction of single functionally defined neurons. Nature Communications. 13(1):Article 1531. https://doi.org/10.1038/s41467-022-29229-0He C, Li Q, Cui Y, Gao P, Shu W, Zhou Q, Wang L, Li L, Lu Z, Zhao Y, et al. 2022. Recurrent moderate hypoglycemia accelerates the progression of Alzheimer's disease through impairment of the TRPC6/GLUT3 pathway. JCI Insight. 7(5):Article e154595. https://doi.org/10.1172/jci.insight.154595Zhang J, He Y, Liang S, Liao X, Li T, Qiao Z, Chang C, Jia H, Chen X. 2021. Non-invasive, opsin-free mid-infrared modulation activates cortical neurons and accelerates associative learning. Nature Communications. 12(1):2730. https://doi.org/10.1038/s41467-021-23025-yLi Z, Wu M, Yao J, Guo J, Liao X, Song S, Li J, Duan G, Zhou Y, Wu X, et al. 2020. Caution on Kidney Dysfunctions of COVID-19 Patients. medRxiv. https://doi.org/10.1101/2020.02.08.20021212Yang M, Zhou Z, Zhang J, Jia S, Li T, Guan J, Liao X, Leng B, Lyu J, Zhang K, et al. 2019. MATRIEX imaging: multiarea two-photon real-time in vivo explorer. Light: Science and Applications. 8(1):Article 109. https://doi.org/10.1038/s41377-019-0219-xYao J, Zhang Q, Liao X, Li Q, Liang S, Li X, Zhang Y, Li X, Wang H, Qin H, et al. 2018. A corticopontine circuit for initiation of urination. Nature Neuroscience. 21(11):1541-1550. https://doi.org/10.1038/s41593-018-0256-4Li Q, Jin R, Yu H, Lang H, Cui Y, Xiong S, Sun F, He C, Liu D, Jia H, et al. 2018. Enhancement of Neural Salty Preference in Obesity. Cellular Physiology and Biochemistry. 43(5):1987-2000. https://doi.org/10.1159/000484122Guan J, Li J, Liang S, Li R, Li X, Shi X, Huang C, Zhang J, Pan J, Jia H, et al. 2018. NeuroSeg: automated cell detection and segmentation for in vivo two-photon Ca2+ imaging data. Brain Structure and Function. 223(1):519-533. https://doi.org/10.1007/s00429-017-1545-5Zhang Q, Yao J, Guang Y, Liang S, Guan J, Qin H, Liao X, Jin W, Zhang J, Pan J, et al. 2017. Locomotion-related population cortical Ca2+ transients in freely behaving mice. Frontiers in Neural Circuits. 11:Article 24. https://doi.org/10.3389/fncir.2017.00024Li Q, Cui Y, Jin R, Lang H, Yu H, Sun F, He C, Ma T, Li Y, Zhou X, et al. 2017. Enjoyment of spicy flavor enhances central salty-taste perception and reduces salt intake and blood pressure. Hypertension. 70(6):1291-1299. https://doi.org/10.1161/HYPERTENSIONAHA.117.09950Jia H, Varga Z, Sakmann B, Konnerth A. 2014. Linear integration of spine Ca2+ signals in layer 4 cortical neurons in vivo. Proceedings of the National Academy of Sciences of the United States of America. 111(25):9277-9282. https://doi.org/10.1073/pnas.1408525111Chen X, Leischner U, Varga Z, Jia H, Deca D, Rochefort NL, Konnerth A. 2012. LOTOS-based two-photon calcium imaging of dendritic spines in vivo. Nature Protocols. 7(10):1818-1829. https://doi.org/10.1038/nprot.2012.106Jia H, Rochefort NL, Chen X, Konnerth A. 2011. In vivo two-photon imaging of sensory-evoked dendritic calcium signals in cortical neurons. Nature Protocols. 6(1):28-35. https://doi.org/10.1038/nprot.2010.169Rochefort NL, Jia H, Konnerth A. 2008. Calcium imaging in the living brain: prospects for molecular medicine. Trends in Molecular Medicine. 14(9):389-399. https://doi.org/10.1016/j.molmed.2008.07.005

