LIN Personal

Dr. Pingan Yuanxiang

Wissenschaftlerin

Neuroplastizität

Leibniz-Institut für Neurobiologie
Brenneckestr. 6
39118 Magdeburg
Deutschland
Telefon: +49 391 6263 94331
E-Mail: Pingan.Yuanxiang@lin-magdeburg.de
ORCID: 0000-0002-3746-3282

  • Publikationen

    Publikationen

    Arndt H, Bachurski M, Yuanxiang P, Franke K, Wessjohann LA, Kreutz MR, Grochowska KM. 2024. A Screen of Plant-Based Natural Products Revealed That Quercetin Prevents Pyroglutamylated Amyloid-β (Aβ3(pE)-42) Uptake in Astrocytes As Well As Resulting Astrogliosis and Synaptic Dysfunction. Molecular Neurobiology. https://doi.org/10.1007/s12035-024-04509-6

    Karpova A, Samer S, Turacak R, Yuanxiang P, Kreutz MR. 2023. Integration of nuclear Ca2+ transients and subnuclear protein shuttling provides a novel mechanism for the regulation of CREB-dependent gene expression. Cellular and Molecular Life Sciences. 80(8):Article 228. https://doi.org/10.1007/s00018-023-04876-8

    Grochowska KM, Gomes GM, Raman R, Kaushik R, Sosulina L, Kaneko H, Oelschlegel AM, Yuanxiang P, Reyes-Resina I, Bayraktar G, et al. 2023. Jacob-induced transcriptional inactivation of CREB promotes Aβ-induced synapse loss in Alzheimer's disease. The EMBO journal. 42(4):Article e112453. https://doi.org/10.15252/embj.2022112453

    Muhia M, YuanXiang P, Sedlacik J, Schwarz JR, Heisler FF, Gromova KV, Thies E, Breiden P, Pechmann Y, Kreutz MR, et al. 2022. Muskelin regulates actin-dependent synaptic changes and intrinsic brain activity relevant to behavioral and cognitive processes. Communications biology. 5(1):Article 589. https://doi.org/10.1038/s42003-022-03446-1

    Confettura AD, Cuboni E, Ammar MR, Jia S, Gomes GM, Yuanxiang P, Raman R, Li T, Grochowska KM, Ahrends R, et al. 2022. Neddylation-dependent protein degradation is a nexus between synaptic insulin resistance, neuroinflammation and Alzheimer's disease. Translational neurodegeneration. 11(1):Article 2. https://doi.org/10.1186/s40035-021-00277-8

    Borgmeyer M, Coman C, Has C, Schött H-F, Li T, Westhoff P, Cheung YFH, Hoffmann N, Yuanxiang P, Behnisch T, et al. 2021. Multiomics of synaptic junctions reveals altered lipid metabolism and signaling following environmental enrichment. Cell Reports. 37(1):Article 109797. https://doi.org/10.1016/j.celrep.2021.109797

    Madencioglu DA, Çalışkan G, Yuanxiang P, Rehberg K, Demiray YE, Kul E, Engler A, Hayani H, Bergado-Acosta JR, Kummer A, et al. 2021. Transgenic modeling of Ndr2 gene amplification reveals disturbance of hippocampus circuitry and function. iScience. 24(8):102868. https://doi.org/10.1016/j.isci.2021.102868

    Lin X, Brunk MGK, Yuanxiang P, Curran AW, Zhang E, Stöber F, Goldschmidt J, Gundelfinger ED, Vollmer M, Happel MFK, et al. 2021. Neuroplastin expression is essential for hearing and hair cell PMCA expression. Brain Structure and Function. 226(5):1533-1551. https://doi.org/10.1007/s00429-021-02269-w

    Bayraktar G, Yuanxiang P, Confettura AD, Gomes GM, Raza SA, Stork O, Tajima S, Suetake I, Karpova A, Yildirim F, et al. 2020. Synaptic control of DNA methylation involves activity-dependent degradation of DNMT3A1 in the nucleus. Neuropsychopharmacology. 45(12):2120-2130. https://doi.org/10.1038/s41386-020-0780-2

    Andres-Alonso M, Ammar MR, Butnaru I, Gomes GM, Acuña Sanhueza G, Raman R, Yuanxiang P, Borgmeyer M, Lopez-Rojas J, Raza SA, et al. 2019. SIPA1L2 controls trafficking and local signaling of TrkB-containing amphisomes at presynaptic terminals. Nature Communications. 10(1):Article 5448. https://doi.org/10.1038/s41467-019-13224-z

    Mikhaylova M, Bär J, van Bommel B, Schätzle P, YuanXiang PA, Raman R, Hradsky J, Konietzny A, Loktionov EY, Reddy PP, et al. 2018. Caldendrin Directly Couples Postsynaptic Calcium Signals to Actin Remodeling in Dendritic Spines. Neuron. 97(5):1110-1125.e14. https://doi.org/10.1016/j.neuron.2018.01.046

    Grochowska KM, Yuanxiang P, Bär J, Raman R, Brugal G, Sahu G, Schweizer M, Bikbaev A, Schilling S, Demuth HU, et al. 2017. Posttranslational modification impact on the mechanism by which amyloid-β induces synaptic dysfunction. EMBO Reports. 18(6):962-981. https://doi.org/10.15252/embr.201643519

    Melgarejo da Rosa M, Yuanxiang PA, Brambilla R, Kreutz MR, Karpova A. 2016. Synaptic GluN2B/CaMKII-α signaling induces synapto-nuclear transport of ERK and jacob. Frontiers in Molecular Neuroscience. 9(AUG):Article 66. https://doi.org/10.3389/fnmol.2016.00066

    Yuan Xiang P, Janc O, Grochowska KM, Kreutz MR, Reymann KG. 2016. Dopamine agonists rescue Aβ-induced LTP impairment by Src-family tyrosine kinases. Neurobiology of Aging. 40:98-102. https://doi.org/10.1016/j.neurobiolaging.2016.01.008

    Spilker C, Nullmeier S, Grochowska KM, Schumacher A, Butnaru I, Macharadze T, Gomes GM, YuanXiang P, Bayraktar G, Rodenstein C, et al. 2016. A Jacob/Nsmf Gene Knockout Results in Hippocampal Dysplasia and Impaired BDNF Signaling in Dendritogenesis. PLoS Genetics. 12(3):Article e1005907. https://doi.org/10.1371/journal.pgen.1005907

    Yuanxiang P, Bera S, Karpova A, Kreutz MR, Mikhaylova M. 2014. Isolation of CA1 nuclear enriched fractions from hippocampal slices to study activity-dependent nuclear import of synapto-nuclear messenger proteins. Journal of Visualized Experiments. (90):Article e51310. https://doi.org/10.3791/51310

    Mikhaylova M, Karpova A, Bär J, Bethge P, YuanXiang P, Chen Y, Zuschratter W, Behnisch T, Kreutz MR. 2014. Cellular distribution of the NMDA-receptor activated synapto-nuclear messenger Jacob in the rat brain. Brain Structure and Function. 219(3):843-860. https://doi.org/10.1007/s00429-013-0539-1

    Chen Y, Yuanxiang P, Knöpfel T, Thomas U, Behnisch T. 2012. Hippocampal LTP triggers proteasome-mediated SPAR degradation in CA1 neurons. Synapse. 66(2):142-150. https://doi.org/10.1002/syn.20994

    Behnisch T, YuanXiang P, Bethge P, Parvez S, Chen Y, Yu J, Karpova A, Frey JU, Mikhaylova M, Kreutz MR. 2011. Nuclear translocation of Jacob in hippocampal neurons after stimuli inducing long-term potentiation but not long-term depression. PLoS ONE. 6(2):e17276. https://doi.org/10.1371/journal.pone.0017276
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