LIN Personal

Dr. Wilko Altrock

Labormanagement

Stab

Leibniz-Institut für Neurobiologie
Brenneckestr. 6
39118 Magdeburg
Deutschland
Telefon: +49 391 6263 93331
E-Mail: Wilko.Altrock@lin-magdeburg.de

  • Publikationen

    Publikationen

    Giniatullina A, Maroteaux G, Geerts CJ, Koopmans B, Loos M, Klaassen R, Chen N, van der Schors RC, van Nierop P, Li KW, de Jong J, Altrock WD, Cornelisse LN, Toonen RF, van der Sluis S, Sullivan PF, Stiedl O, Posthuma D, Smit AB, Groffen AJ, Verhage M. 2015. Functional characterization of the PCLO p.Ser4814Ala variant associated with major depressive disorder reveals cellular but not behavioral differences. Neuroscience. 300:518-538. https://doi.org/10.1016/j.neuroscience.2015.05.047

    Ivanova D, Dirks A, Montenegro-Venegas C, Schöne C, Altrock WD, Marini C, Frischknecht R, Schanze D, Zenker M, Gundelfinger ED, Fejtova A. 2015. Synaptic activity controls localization and function of CtBP1 via binding to Bassoon and Piccolo. EMBO Journal. 34(8):1056-1077. https://doi.org/10.15252/embj.201488796

    Davydova D, Marini C, King C, Klueva J, Bischof F, Romorini S, Montenegro-Venegas C, Heine M, Schneider R, Schroeder M, Altrock WD, Henneberger C, Rusakov DA, Gundelfinger ED, Fejtova A. 2014. Bassoon specifically controls presynaptic P/Q-type Ca2+ channels via RIM-binding protein. Neuron. 82(1):181-194. https://doi.org/10.1016/j.neuron.2014.02.012

    Waites CL, Leal-Ortiz SA, Okerlund N, Dalke H, Fejtova A, Altrock WD, Gundelfinger ED, Garner CC. 2013. Bassoon and Piccolo maintain synapse integrity by regulating protein ubiquitination and degradation. EMBO Journal. 32(7):954-969. https://doi.org/10.1038/emboj.2013.27

    Schroeder M, Stellmacher A, Romorini S, Marini C, Montenegro-Venegas C, Altrock WD, Gundelfinger ED, Fejtova A. 2013. Regulation of Presynaptic Anchoring of the Scaffold Protein Bassoon by Phosphorylation-Dependent Interaction with 14-3-3 Adaptor Proteins. PLoS ONE. 8(3):e58814. https://doi.org/10.1371/journal.pone.0058814

    Maas C, Torres VI, Altrock WD, Leal-Ortiz S, Wagh D, Terry-Lorenzo RT, Fejtova A, Gundelfinger ED, Ziv NE, Garner CC. 2012. Formation of Golgi-derived active zone precursor vesicles. Journal of Neuroscience. 32(32):11095-11108. https://doi.org/10.1523/JNEUROSCI.0195-12.2012

    Hübler D, Rankovic M, Richter K, Lazarevic V, Altrock WD, Fischer KD, Gundelfinger ED, Fejtova A. 2012. Differential spatial expression and subcellular localization of CtBP family members in Rodent Brain. PLoS ONE. 7(6):e39710. https://doi.org/10.1371/journal.pone.0039710

    Dondzillo A, Sätzler K, Horstmann H, Altrock WD, Gundelfinger ED, Kuner T. 2010. Targeted three-dimensional immunohistochemistry reveals localization of presynaptic proteins Bassoon and Piccolo in the rat calyx of held before and after the onset of hearing. Journal of Comparative Neurology. 518(7):1008-1029. https://doi.org/10.1002/cne.22260

    Goetze B, Schmidt KF, Lehmann K, Altrock WD, Gundelfinger ED, Löwel S. 2010. Vision and visual cortical maps in mice with a photoreceptor synaptopathy: Reduced but robust visual capabilities in the absence of synaptic ribbons. NeuroImage. 49(2):1622-1631. https://doi.org/10.1016/j.neuroimage.2009.10.019

    Ghiglieri V, Picconi B, Sgobio C, Bagetta V, Barone I, Paillè V, Di Filippo M, Polli F, Gardoni F, Altrock W, Gundelfinger ED, De Sarro G, Bernardi G, Ammassari-Teule M, Di Luca M, Calabresi P. 2009. Epilepsy-induced abnormal striatal plasticity in Bassoon mutant mice. European Journal of Neuroscience. 29(10):1979-1993. https://doi.org/10.1111/j.1460-9568.2009.06733.x

    Fejtova A, Davydova D, Bischof F, Lazarevic V, Altrock WD, Romorini S, Schöne C, Zuschratter W, Kreutz MR, Garner CC, Ziv NE, Gundelfinger ED. 2009. Dynein light chain regulates axonal trafficking and synaptic levels of Bassoon. Journal of Cell Biology. 185(2):341-355. https://doi.org/10.1083/jcb.200807155

    Gundelfinger ED, Altrock WD, Fejtová A. 2009. Active zone. Binder MD, Hirokawa N, Windhorst U, editors. In Encyclopedia of Neuroscience. Berlin, Heidelberg: Springer. pp. 44-49.

    Angenstein F, Hilfert L, Zuschratter W, Altrock WD, Niessen HG, Gundelfinger ED. 2008. Morphological and metabolic changes in the cortex of mice lacking the functional presynaptic active zone protein bassoon: A combined 1H-NMR spectroscopy and histochemical study. Cerebral Cortex. 18(4):890-897. https://doi.org/10.1093/cercor/bhm122

    Jose M, Nair DK, Altrock WD, Dresbach T, Gundelfinger ED, Zuschratter W. 2008. Investigating interactions mediated by the presynaptic protein bassoon in living cells by foerster's resonance energy transfer and fluorescence lifetime imaging microscopy. Biophysical Journal. 94(4):1483-1496. https://doi.org/10.1529/biophysj.107.111674

    Gong J, Jellali A, Forster V, Mutterer J, Dubus E, Altrock WD, Sahel JA, Rendon A, Picaud S. 2007. The toxicity of the PrP106-126 prion peptide on cultured photoreceptors correlates with the prion protein distribution in the mammalian and human retina. American Journal of Pathology. 170(4):1314-1324. https://doi.org/10.2353/ajpath.2007.060340

    Angenstein F, Niessen HG, Goldschmidt J, Lison H, Altrock WD, Gundelfinger ED, Scheich H. 2007. Manganese-enhanced MRI reveals structural and functional changes in the cortex of bassoon mutant mice. Cerebral Cortex. 17(1):28-36. https://doi.org/10.1093/cercor/bhj121

    Dresbach T, Torres V, Wittenmayer N, Altrock WD, Zamorano P, Zuschratter W, Nawrotzki R, Ziv NE, Garner CC, Gundelfinger ED. 2006. Assembly of active zone precursor vesicles: Obligatory trafficking of presynaptic cytomatrix proteins Bassoon and Piccolo via A trans-Golgi compartment. Journal of Biological Chemistry. 281(9):6038-6047. https://doi.org/10.1074/jbc.M508784200

    Jastrow H, Koulen P, Altrock WD, Kröger S. 2006. Identification of a β-dystroglycan immunoreactive subcompartment in photoreceptor terminals. Investigative Ophthalmology and Visual Science. 47(1):17-24. https://doi.org/10.1167/iovs.05-0597

    Tom Dieck S, Altrock WD, Kessels MM, Qualmann B, Regus H, Brauner D, Fejtová A, Bracko O, Gundelfinger ED, Brandstätter JH. 2005. Molecular dissection of the photoreceptor ribbon synapse: Physical interaction of Bassoon and RIBEYE is essential for the assembly of the ribbon complex. Journal of Cell Biology. 168(5):825-836. https://doi.org/10.1083/jcb.200408157

    Dresbach T, Hempelmann A, Spilker C, Tom Dieck S, Altrock WD, Zuschratter W, Garner CC, Gundelfinger ED. 2003. Functional regions of the presynaptic cytomatrix protein Bassoon: Significance for synaptic targeting and cytomatrix anchoring. Molecular and Cellular Neurosciences. 23(2):279-291. https://doi.org/10.1016/S1044-7431(03)00015-0

    Altrock WD, Tom Dieck S, Sokolov M, Meyer AC, Sigler A, Brakebusch C, Fässler R, Richter K, Boeckers TM, Potschka H, Brandt C, Löscher W, Grimberg D, Dresbach T, Hempelmann A, Hassan H, Balschun D, Frey JU, Brandstätter JH, Garner CC, Rosenmund C, Gundelfinger ED. 2003. Functional inactivation of a fraction of excitatory synapses in mice deficient for the active zone protein bassoon. Neuron. 37(5):787-800. https://doi.org/10.1016/S0896-6273(03)00088-6

    Dick O, Tom Dieck S, Altrock WD, Ammermüller J, Weiler R, Garner CC, Gundelfinger ED, Brandstätter JH. 2003. The presynaptic active zone protein bassoon is essential for photoreceptor ribbon synapse formation in the retina. Neuron. 37(5):775-786. https://doi.org/10.1016/S0896-6273(03)00086-2

    Kim S, Ko J, Shin H, Lee JR, Lim C, Han JH, Altrock WD, Garner CC, Gundelfinger ED, Premont RT, Kaang BK, Kim E. 2003. The GIT family of proteins forms multimers and associates with the presynaptic cytomatrix protein piccolo. Journal of Biological Chemistry. 278(8):6291-6300. https://doi.org/10.1074/jbc.M212287200

    Dresbach T, Altrock WD, Gundelfinger ED. 2003. Neurotransmitterfreisetzung an chemischen Synapsen: Zusammenbau und molekulare Organisation der aktiven Zone. Neuroforum. 3:79-86.

    Dick O, Hack I, Altrock WD, Garner CC, Gundelfinger ED, Brandstätter JH. 2001. Localization of the presynaptic cytomatrix protein Piccolo at ribbon and conventional synapses in the rat retina: Comparison with Bassoon. Journal of Comparative Neurology. 439(2):224-234. https://doi.org/10.1002/cne.1344

    Helmuth M, Altrock W, Böckers TM, Gundelfinger ED, Kreutz MR. 2001. An electrotransfection protocol for yeast two-hybrid library screening. Analytical Biochemistry. 293(1):149-152. https://doi.org/10.1006/abio.2001.5107

    Sanmartí-Vila L, Tom Dieck S, Richter K, Altrock W, Zhang L, Volknandt W, Zimmermann H, Garner CC, Gundelfinger ED, Dresbach T. 2000. Membrane association of presynaptic cytomatrix protein Bassoon. Biochemical and Biophysical Research Communications. 275(1):43-46. https://doi.org/10.1006/bbrc.2000.3256

    Winter C, Tom Dieck S, Boeckers TM, Bockmann J, Kämpf U, Sanmartí-Vila L, Langnaese K, Altrock W, Stumm M, Soyke A, Wieacker P, Garner CC, Gundelfinger ED. 1999. The presynaptic cytomatrix protein Bassoon: Sequence and chromosomal localization of the human BSN gene. Genomics. 57(3):389-397. https://doi.org/10.1006/geno.1999.5788
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